Ophthalmic Case Studies and Novel Approach


In a small randomized controlled trial, production of aqueous tears and secretion of goblet cells increased following application of the Oculeve Intranasal Lacrimal Neurostimulator (Allergan).1 This handheld device works by delivering electrical stimulation to the anterior ethmoidal branch of the trigeminal nerve in the nasal cavities. It potentially offers a new mechanism for treating dry eye disease—now largely managed with artificial tears and anti-inflammatory agents.


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